Allgemeine zellbasierte Assays

Allgemeine zellbasierte Assays
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Thermo Scientific™ Kinase Tracer 236, 50 μM
Im LanthaScreen™ Eu-Kinase-Bindungsassay wird die Bindung eines Alexa Fluor™ Konjugats oder einer Markierungssubstanz wie der Kinase Markierungssubstanz 236 an eine Kinase durch Zugabe eines mit Eu markierten Anti-Tag-Antikörpers nachgewiesen.
Thermo Scientific™ CellSensor™ CRE-bla Jurkat-Zelllinie
The CRE-bla Jurkat cell line contains a beta-lactamase reporter gene under control of a cAMP response element (CRE) stably integrated into Jurkat cells.
Thermo Scientific™ LanthaScreen™ STAT5 TF-1-Zelllinie
LanthaScreen™ GFP Cellular Assays allow for the analysis of post-translational modifications for a number of target proteins in an live-cell context.
Thermo Scientific™ CellSensor™ TrkA-NFAT-bla CHO-K1-Zelllinie
Neurotrophins (NGF, BDNF, NT-3, and NT-4) and their transmembrane receptors (TrkA, TrkB, TrkC, and P75NTR) play important roles in the regulation of neuronal and non-neuronal cell proliferation, differentiation, survival, and death.
Thermo Scientific™ Tango™ CCR5-bla U2OS Cells
The Tango™ CCR5-bla U2OS cells contain the human Chemokine (C-C Motif) Receptor 5 (CCR5) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Alexa Fluor™ Kinase Tracer 1710, 25 μM
Alexa Fluor™ Kinase Markierungssubstanz 1710 wird durch Zugabe eines mit Eu-markierten Anti-Tag-Antikörpers nachgewiesen.
Alexa Fluor™ Kinase Tracer 314, 25 μM
Alexa Fluor™ Kinase Markierungssubstanz 315 wird durch Zugabe eines mit Eu-markierten Anti-Tag-Antikörpers nachgewiesen.
Thermo Scientific™ Tango™ ADRA2A-bla U2OS DA Assay-Kit
The Tango™ ADRA2A-bla U2OS cells contain the human Adrenergic, Alpha-2A-, Receptor (ADRA2A) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ GeneBLAzer™ GRPR CHO-K1 DA Assay Kit
The GeneBLAzer™ GRPR-NFAT-bla CHO-K1 cells contain the human Gastrin Releasing Peptide Receptor (GRPR) stably integrated into the GeneBLAzer™ NFAT-bla CHO-K1 cell line.
Thermo Scientific™ CellSensor™ c-Fos-bla HEK293T Cell Line
Die c-Fos-bla HEK 293T-Zelllinie enthält ein Beta-Lactamase-Reportergen, das unter Kontrolle des c-Fos-Promotors steht, welcher stabil in HEK 293T-Zellen integriert ist.
Thermo Scientific™ GeneBLAzer™ C5AR1-Gα15 CHO-K1 DA Assay-Kit
The GeneBLAzer™ C5AR1-Gα15 CHO-K1 DA (Division Arrested) cells contain the human Complement Component 5a Receptor 1 (C5AR1) stably integrated into the GeneBLAzer™ Gα15-NFAT-bla CHO-K1 cell line.
Thermo Scientific™ Tango™ CCR6-bla U2OS DA Assay Kit
Die Tango™ CCR6-bla U2OS-Zellen enthalten den humanen Chemokin (C-C-Motiv)-Rezeptor 6 (CCR6), der mit einer TEV-Proteasestelle und einem Gal4-VP16-Transkriptionsfaktor verknüpft und stabil in die parentale Tango™ GPCR-bla U2OS-Zelllinie integriert ist.
Thermo Scientific™ GeneBLAzer™ NTSR1 CHO-K1 DA Assay Kit
The GeneBLAzer™ NTSR1 CHO-K1 DA cells contain the human Neurotensin Receptor 1 (NTSR1) stably integrated into the GeneBLAzer™ Gqo5-NFAT-bla CHO-K1 cell line.
Thermo Scientific™ Tango™ HTR2A-bla U2OS-Zellen
The Tango™ HTR2A-bla U2OS cells contain the human Serotonin Type 2A receptor (HTR2A) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ CellSensor™ SIE-bla ME-180 Cell Line
The CellSensor&tarde; SIE-bla ME-180 cell line contains a beta-lactamase reporter gene under control of the Sis-Inducible Element (SIE) stably integrated into ME-180 cells.