missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Thermo Scientific™ CellSensor™ SIE-bla ME-180 Cell Line
The CellSensor&tarde; SIE-bla ME-180 cell line contains a beta-lactamase reporter gene under control of the Sis-Inducible Element (SIE) stably integrated into ME-180 cells.
Marke: Thermo Scientific™ K1648
Dieser Artikel kann nicht zurückgegeben werden.
Rückgaberichtlinie anzeigen
Beschreibung
The CellSensor&tarde; SIE-bla ME-180 cell line contains a beta-lactamase reporter gene under control of the Sis-Inducible Element (SIE) stably integrated into ME-180 cells. To construct this cell line, the SIE-bla construct was transduced into ME-180 cells by lentivirus. Flow cytometry was used to isolate cells responsive to Interleukin-6 (IL-6). This cell line is validated for DMSO tolerance, cell number, stimulation time, substrate loading time, as well as Z' and EC50 concentrations of IL-6. The CellSensor™ SIE-bla ME-180 cell line is responsive to IL-6, OSM and IFNγ and can be used to probe the JAK/STAT signaling pathway. This cell line can be adapted for high-throughput screening of agonist or antagonist compound libraries. Candidate drugs can also be tested for dose response against this cell line. Academic and non-profit customers, please inquire for special pricing.
Spezifikation
| Zellbasiertes Beta-Lactamase-Reportergen | |
| CellSensor™ Zelllinien werden auf Trockeneis geliefert. Sofort nach Erhalt in Flüssigstickstoff lagern oder zur sofortigen Verwendung auftauen. | |
| CellSensor™ | |
| STAT1, STAT3, JAK/STAT (IFN-gamma, IL-6/OSM) Signalweg, JAK2, JAK1 | |
| CellSensor™ |
| Teilende Zellen | |
| Signalweg | |
| 1 Fläschchen | |
| Teilende Zellen | |
| Signalweg |
Nur für Forschungszwecke. Nicht zur Verwendung bei diagnostischen Verfahren.