Allgemeine zellbasierte Assays
Allgemeine zellbasierte Assays
Thermo Scientific™ Tango™ CCR1-bla U2OS Cells
The Tango™ CCR1 -bla U2OS cells contain the human Chemokine (C-C Motif) Receptor 1 (CCR1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ CellSensor™ p53RE-bla HCT-116 Cell Line
The CellSensor™ p53RE-bla HCT-116 cell line contains a beta-lactamase reporter gene under control of the p53 response element stably integrated into HCT-116 cells.
Thermo Scientific™ GeneBLAzer™ ADRA1A CHO-K1-DA-Assay-Kit
The GeneBLAzer™ ADRA1A CHO-K1 DA (Division Arrested) cells contain the human Adrenergic Alpha-1A Receptor (ADRA1A), stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.
Thermo Scientific™ GeneBLAzer™ LXRα-UAS-bla HEK 293T Cells
LXR alpha-UAS-bla HEK 293T 293 cells contain the ligand-binding domain (LBD) of the human Liver-X receptor-alpha(LXR alpha) fused to the DNA-binding domain of GAL4 stably integrated in the GeneBLAzer™UAS-bla HEK 293T cell line.
Thermo Scientific™ CellSensor™ CRE-bla CHO K1-Zelllinie
The CellSensor™ CRE-bla CHO-K1 cell line contains a beta-lactamase reporter gene under control of a cAMP response element (CRE) stably integrated into CHO-K1 cells.
Thermo Scientific™ GeneBLAzer™ P2RY6 CHO-K1 DA Assay Kit
GeneBLAzer™ P2RY6 CHO-K1 DA (Division Arrested) cells and P2RY6-NFAT-bla CHO-K1 cells contain the human purinergic receptor P2, G protein-coupled, 6 (P2RY6) receptor stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.
Thermo Scientific™ CellSensor™ HRE-bla HCT-116 Cell Line
The CellSensor™ HRE-bla HCT-116 Cell Line contains a beta-lactamase reporter gene under control of the HRE stably integrated into HCT-116 cells. This cell line is validated for EC50 and Z'-factor under optimized conditions using deferoxamine (DFO) and Cobalt Chloride.
Thermo Scientific™ GeneBLAzer™ P2RY4-NFAT-bla CHO-K1 Cells
GeneBLAzer™ P2RY4-NFAT-bla CHO-K1 cells contain the human Purinergic Receptor P2Y4 (P2RY4), stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.
Thermo Scientific™ CellSensor™ ISRE-bla HEK293T Cell Line
The CellSensor™ ISRE-bla HEK 293T cell line is responsive to interferon alpha and can be used to probe the JAK/STAT signaling pathway.
Alexa Fluor™ Kinase Tracer 1710, 25 μM
Alexa Fluor™ Kinase Markierungssubstanz 1710 wird durch Zugabe eines mit Eu-markierten Anti-Tag-Antikörpers nachgewiesen.
Thermo Scientific™ GeneBLAzer™ Gα15-NFAT-bla CHO-K1-Zellen
The GeneBLAzer™ Gα15-NFAT-bla CHO-K1 cell line contains the promiscuous Gα protein, Gα15, stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.
Thermo Scientific™ CellSensor™ SBE-bla A375 Cell Line
Bone morphogenetic proteins (BMPs), members of the transforming growth factor beta (TGF-β) superfamily, play important roles in the development of the heart, central nervous system and cartilage.
Thermo Scientific™ GeneBLAzer™ Gqi5-NFAT-bla FreeStyle™ 293F Cells
GeneBLAzer™ Gqi5-NFAT-bla FreeStyle™ 293F cells contain the chimeric G-protein Gqi5 stably integrated into the CellSensor™ NFAT-blaFreeStyle™ 293F cell line.
Thermo Scientific™ GeneBLAzer™ OPRL1-Gqi5-NFAT-bla FreeStyle™ 293F Cells
The GeneBLAzer™ OPRL1-Gqi5-NFAT-bla FreeStyle™ 293F Cell Line contains the human opioid/opiate receptor-like-1 receptor (OPRL1) stably integrated into the GeneBLAzer™ Gqi5-NFAT-bla FreeStyle™ 293F Cell Line.
Thermo Scientific™ GeneBLAzer™ EDNRA-NFAT-bla HEK 293T Cells
Bei GeneBLAzer™ EDNRA-NFAT-bla HEK293T-Zellen ist der humane Endothelin-Rezeptor Typ A (EDNRA) stabil in die CellSensor™ NFAT-bla HEK293T-Zelllinie integriert.