Allgemeine zellbasierte Assays

Allgemeine zellbasierte Assays
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Thermo Scientific™ Kinase Tracer 236, 50 μM
Im LanthaScreen™ Eu-Kinase-Bindungsassay wird die Bindung eines Alexa Fluor™ Konjugats oder einer Markierungssubstanz wie der Kinase Markierungssubstanz 236 an eine Kinase durch Zugabe eines mit Eu markierten Anti-Tag-Antikörpers nachgewiesen.
Thermo Scientific™ LanthaScreen™ STAT1 U2OS Cell Line
The JAK/STAT1 signaling pathway is known to be activated by type I/II interferons such as interferon-gamma and interferon-alpha.
Thermo Scientific™ Tango™ AGTRL1-bla U2OS Cells
The Tango™ AGTRL1-bla U2OS cells contain the human Angtiotension-Like Receptor 1 (AGTRL1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ CellSensor™ CRE-bla Jurkat-Zelllinie
The CRE-bla Jurkat cell line contains a beta-lactamase reporter gene under control of a cAMP response element (CRE) stably integrated into Jurkat cells.
Thermo Scientific™ LanthaScreen™ STAT5 TF-1-Zelllinie
LanthaScreen™ GFP Cellular Assays allow for the analysis of post-translational modifications for a number of target proteins in an live-cell context.
Thermo Scientific™ CellSensor™ TrkA-NFAT-bla CHO-K1-Zelllinie
Neurotrophins (NGF, BDNF, NT-3, and NT-4) and their transmembrane receptors (TrkA, TrkB, TrkC, and P75NTR) play important roles in the regulation of neuronal and non-neuronal cell proliferation, differentiation, survival, and death.
Thermo Scientific™ GeneBLAzer™ EDG3-Gα15 HEK 293T DA Assay Kit
GeneBLAzer™ EDG3-Gα15 HEK 293T DA (Division Arrested) cells and EDG3-Gα15-NFAT-bla HEK 293T cells contain the human EDG3 receptor stably integrated in the GeneBLAzer™ Gα15-NFAT-bla HEK 293T cell line.
Thermo Scientific™ Tango™ CCR5-bla U2OS Cells
The Tango™ CCR5-bla U2OS cells contain the human Chemokine (C-C Motif) Receptor 5 (CCR5) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ CellSensor™ IL1-bla ECV304 Cell Line
The CellSensor™ IL-1-bla ECV304 cell line is an adherent human urinary bladder cell line used to measure the (IL-1) signaling pathway via transcriptional regulation of the beta-lactamase gene.
Thermo Scientific™ Tango™ EDG4-bla U2OS Cells
The Tango™ EDG4-bla U2OS cells contain the human Endothelial Differentiation Gene 4 (EDG4) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ GeneBLAzer™ NMUR1-NFAT-bla CHO-K1 Cells
GeneBLAzer™ NMUR1-NFAT-bla CHO-K1 cells contain the human Neuromedin U-25 receptor 1 (NMUR1) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.
Thermo Scientific™ CellSensor™ NFAT CHO-K1 DA Assay-Kit
The CellSensor™ NFAT CHO-K1 DA (Division Arrested) cells contain a beta-lactamase (bla) reporter gene under control of a Nuclear Factor of Activated T Cells (NFAT) response element stably integrated into CHO-K1 cells.
Thermo Scientific™ GeneBLAzer™ H1-NFAT-bla HEK 293T Cells
GeneBLAzer™ H1-NFAT-bla HEK293T cells contain the human Histamine Receptor 1 (H1) stably integrated into the CellSensor™ NFAT-bla HEK293T cell line.
Thermo Scientific™ Tango™ CXCR1-bla U2OS-Zellen
The Tango™ CXCR1-bla U2OS cells contain the human Chemokine (C-X-C motif) receptor 1 (CXCR1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.