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R&D Systems™ Recombinant Mouse PDGF R beta Fc Chimera Protein
Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility. Applications: Bioactivity
Marke: R&D Systems™ 1042-PR-100
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Beschreibung
Measured by its ability to inhibit the biological activity of PDGF-BB using NR6R-3T3 mouse fibroblast cells. Raines, E.W. et al. (1985) Methods Enzymol. 109:749. The ED50 for this effect is 6-48 ng/mL in the presence of 4 ng/mL recombinant human PDGF-BB.
Spezifikation
P05622 | |
Lyophilized from a 0.2 μm filtered solution in PBS. | |
M.W. (Observed): 124 kDa, reducing conditions; M.W. (theoretical): 82.6 kDa (monomer) | |
100 μg | |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution. | |
<0.10 EU / 1 μg of the protein by the LAL method. | |
Unconjugated | |
Reconstitute at 100 μg/mL in sterile PBS. | |
PDGF R beta |
Bioactivity | |
5159 | |
PDGF R beta Fc Chimera | |
Mouse myeloma cell line, NS0-derived mouse PDGF R beta protein Mouse PDGF R beta (Leu32-Lys530) (N-terminus) Accession # P05622 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus) | |
Disulfide-linked homodimer | |
Pdgfrb | |
Recombinant | |
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain. |
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R&D Systems™ Recombinant Mouse PDGF R beta Fc Chimera Protein > 100ug; Carrier Free
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