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Thermo Scientific™ Tango™ EDG3-bla U2OS Cells
Tango™ EDG3-bla U2OS cells contain the human Endothelial Differentiation Gene 3 (EDG3) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Marke: Thermo Scientific™ K1848
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Beschreibung
Tango™ EDG3-bla U2OS cells contain the human Endothelial Differentiation Gene 3 (EDG3) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase reporter gene under the control of a UAS response element. The Tango™ EDG3-bla U2OS cells have been functionally validated for Z' factor and EC50 concentrations of S1P. In addition, Tango™ EDG3-bla U2OS cells have been tested for assay performance under variable conditions.
Spezifikation
| NM_005226.2 | |
| Teilende Zellen | |
| Nativer Schwanz | |
| FRET | |
| Pool aus stabilen Zellen | |
| 8 x 106 Zellen | |
| BLA (Beta-Lactamase) | |
| Teilende Zellen | |
| Tango™ |
| Zellbasierte Beta-Arrestin-Rekrutierung | |
| Tango™ Zelllinien werden auf Trockeneis versendet. Sofort nach Erhalt in Flüssigstickstoff lagern oder zur sofortigen Verwendung auftauen. | |
| Fluoreszent | |
| G-Protein-gekoppelter Rezeptor (GPCR) | |
| Tango™ | |
| Endpunkt | |
| EDG3 | |
| U2OS | |
| GPCRs |
For Research Use Only. Not for use in diagnostic procedures.