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Gibco™ Human IL-34 Recombinant Protein, PeproTech®
Recombinant Protein
Marke: Gibco™ 200-34-50UG
617.10 CHF gültig bis 2025-06-30
Benutzen Sie den Promotions-Code "24074" um Ihren Promotions-Preis zu erhalten.
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Beschreibung
200-34-1MG will be provided as 2 x 500 μg (200-34-500UG). Recombinant Human IL-34 is a 52.5 kDa homodimeric glycoprotein consisting of 460 amino acid residues, including a C-terminal His-Tag. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
IL-34 is secreted as a dimeric protein and currently belongs to no known cytokine family. It signals via the M-CSF Receptor, also known as CSF-1R and CD115, which is shared with M-CSF. IL-34 has no amino acid sequence homology to M-CSF, but they exhibit similarities in secondary structure and share overlapping functions. IL-34 has been shown to promote myeloid survival, proliferation, and differentiation, and to play a role in osteoclast formation. IL-34 expression has been detected in various tissues and is most abundant in the spleen.
Spezifikation
| Q6ZMJ4 | |
| protein with no preservative | |
| 52.5 kDa | |
| 50 μg | |
| RUO | |
| 2010004A03Rik; AI593503; C16orf77; IL34; IL-34; ILN; Interleukin; interleukin 34; Interleukin34; interleukin-34 | |
| Il34 | |
| Unconjugated | |
| His-tag | |
| -20°C | |
| Lyophilized |
| Functional Assay | |
| 146433 | |
| Human IL-34 | |
| HEK293 cells | |
| <1 EU/ μg | |
| IL-34 | |
| Measured by its ability to induce secretion of MCP-1 from PBMCs. | |
| Recombinant | |
| NEPLEMWPLT QNEECTVTGF LRDKLQYRSR LQYMKHYFPI NYKISVPYEG VFRIANVTRL QRAQVSEREL RYLWVLVSLS ATESVQDVLL EGHPSWKYLQ EVETLLLNVQ QGLTDVEVSP KVESVLSLLN APGPNLKLVR PKALLDNCFR VMELLYCSCC KQSSVLNWQD CEVPSPQSCS PEPSLQYAAT QLYPPPPWSP SSPPHSTGSV RPVRAQGEGL LPHHHHHHHH | |
| HEK293 cells | |
| ≥ 95% by SDS-PAGE gel and HPLC analyses. |
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Gibco™ Human IL-34 Recombinant Protein, PeproTech® > 50 μg; Unlabeled
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