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Thermo Scientific™ EZ-Link™ Maleimide-PEG4-DBCO
A sulfhydryl reactive heterobifunctional crosslinker which contains a dibenzylcyclooctyne (DBCO) group for copper-free click chemistry applications. The thiol/sulfhdryl reactive maleimide can be used to label a variety of thiol containing moieties such as free cystines in proteins, peptides, or other (bio)molecules.
231.00 CHF - 297.00 CHF
Spezifikation
| Chemische Reaktivität | Azid-Thiol |
|---|---|
| Cleavable | Nein |
| Beschreibung | Maleimid-PEG4-DBCO |
| Molekulargewicht | 647,74 |
| PEGyliert | Ja |
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|---|---|---|---|---|---|---|---|---|---|
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|
17611586
|
Thermo Scientific™
C20041 |
10 x 1 mg |
231.00 CHF
25 Milligramm |
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17631586
|
Thermo Scientific™
C20044 |
10 x 1 mg |
297.00 CHF
10 Stück |
Lager vorrätigLoggen Sie sich ein, um den Lagerbestand zu sehen
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Beschreibung
- A sulfhydryl reactive heterobifunctional crosslinker which contains a dibenzylcyclooctyne (DBCO) group for copper-free click chemistry applications
- The thiol/sulfhdryl reactive maleimide can be used to label a variety of thiol containing moieties such as free cystines in proteins, peptides, or other (bio)molecules
- Once a protein or (bio)molecule is DBCO labeled, it can undergo a copper-free azide-alkyne cycloaddition reaction to form a stable triazole linkage with an azide labeled coupling partner
- Can be used to create diverse conjugates with the biorthogonal coupling between an alkyne and azide (supplied separately)
- The coupling or crosslinking procedure is typically done in two steps:
- First, a protein or thiol containing molecule is labeled with a DBCO group and excess crosslinker is removed
- Second, an azide containing moiety (prepared independently) is introduced into the same system as the DBCO moiety
- Labeling occurs under biological conditions without the introduction of any additional reagents such as a copper catalyst
- Reagent readily dissolves in water-miscible solvents for dilution into aqueous reaction mixtures
Spezifikation
| Azid-Thiol | |
| Maleimid-PEG4-DBCO | |
| Ja | |
| Nach Erhalt getrocknet bei -20 °C lagern. | |
| Nasseis | |
| Chemische Markierung | |
| Maleimid, DBCO | |
| 10 x 1 mg | |
| Standard, Einmalgebrauch | |
| Vernetzer |
| Nein | |
| 647,74 | |
| 29,7 Å | |
| Nicht ermittelt | |
| EZ-Link™ No-Weigh™ | |
| Heterobifunktional | |
| Mittel (10 bis 30 Å) | |
| DMF, DMSO | |
| Nein |