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Digoxin, Tocris Bioscience™

Artikelnummer. 18702624
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Menge:
50 mg
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Beschreibung

Na+/K+ ATPase inhibitor

Inhibits membrane-bound α-subunits of the Na+/K+ ATPase pump in myocytes. Increases RGS2 protein levels in primary vascular smooth muscle cells through an Na+/K+ ATPase pump-dependent mechanism. Also exhibits anti-MERS-CoV activity in Vero cells in vitro (IC50 = 0.17 μM).

Spezifikation

Chemischer Name oder Material Digoxin
CAS 20830-75-5
Summenformel C41H64O14
Menge 50 mg
Synonym digoxin, 12beta-hydroxydigitoxin, digoxine, lanoxin, lanoxicaps, digosin, digossina, digoxina, digoxinum, lanoxicaps tn
InChI-Schlüssel LTMHDMANZUZIPE-PUGKRICDSA-N
SMILES CC1C(C(CC(O1)OC2C(OC(CC2O)OC3C(OC(CC3O)OC4CCC5(C(C4)CCC6C5CC(C7(C6(CCC7C8=CC(=O)OC8)O)C)O)C)C)C)O)O
IUPAC-Name 3-[(3S,5R,8R,9S,10S,12R,13S,14S,17R)-3-[(2R,4S,5S,6R)-5-[(2S,4S,5S,6R)-5-[(2S,4S,5S,6R)-4,5-Dihydroxy-6-Methyloxan-2-yl]oxy-4-Hydroxy-6-Methyloxan-2-yl]oxy-4-Hydroxy-6-Methyloxan-2-yl]oxy-12,14-Dihydroxy-10,13-Dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tet
Molekulargewicht (g/mol) 780.949
PubChem CID 2724385
ChEBI CHEBI:4551
Formelmasse 780.94
Reinheit (%) >98%
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