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VU 10010, Tocris Bioscience™

Artikelnummer. 18025522
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Menge:
10 mg
50 mg
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Beschreibung

Selective allosteric potentiator of M4 receptors

Selective allosteric potentiator of M4 acetylcholine receptors (EC50 values are 33 and 0.7 nM for ACh in the absence and presence of VU10010 respectively). Binds to an allosteric site on the receptor increasing affinity for ACh and coupling to G-proteins.

Chemische Identifikatoren

CAS 633283-39-3
Summenformel C17H16ClN3OS
Molekulargewicht (g/mol) 345.845
InChI-Schlüssel FPRULFHDSFKYBV-UHFFFAOYSA-N
Synonym 3-amino-n-4-chlorophenyl methyl-4,6-dimethylthieno 2,3-b pyridine-2-carboxamide, 3-amino-n-4-chlorobenzyl-4,6-dimethylthieno 2,3-b pyridine-2-carboxamide, 2fli, 2-fly, f-ligrlo-nh2, 2-fap, 2-f-ligrlo-nh2, d0n2vn, 2-furoyl-ligrlo-amide trifluoroacetate salt, 2-furoyl-leu-ile-gly-arg-leu-orn-nh2 trifluoroacetate salt
PubChem CID 714286
IUPAC-Name 3-amino-N-[(4-chlorophenyl)methyl]-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide
SMILES CC1=CC(=NC2=C1C(=C(S2)C(=O)NCC3=CC=C(C=C3)Cl)N)C

Spezifikation

Chemischer Name oder Material VU 10010
Menge 10 mg
Formelmasse 345.85
Reinheit (%) >99%
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