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UCB 35625, Tocris Bioscience™

Artikelnummer. 30001389
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Menge:
1 mg
10 mg
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Beschreibung

Potent CCR1 and CCR3 antagonist

Potent chemokine CCR1 and CCR3 receptor antagonist. Inhibits MIP-1α-induced chemotaxis in CCR1 transfectants and eotaxin-induced chemotaxis in CCR3 transfectants (IC50 values are 9.57 and 93.8 nM respectively). Antagonizes CCR3-mediated entry of HIV-1 isolate 89.6 into NP-2 cells (IC50 = 57 nM).

Isomer also available.

Chemische Identifikatoren

CAS 202796-42-7
Summenformel C30H37Cl2IN2O2
Molekulargewicht (g/mol) 655.44
InChI-Schlüssel FOAFBMYSXIGAOX-UHFFFAOYSA-N
Synonym unii-hd099hot7h, unii-h942hgf14d, hd099hot7h, chembl34626, piperidinium, 1-1-cycloocten-1-ylmethyl-4-2,7-dichloro-9h-xanthen-9-yl carbonyl amino-1-ethyl-, iodide 1:1 , cis, piperidinium, 1-1-cycloocten-1-ylmethyl-4-2,7-dichloro-9h-xanthen-9-yl carbonyl amino-1-ethyl-, iodide 1:1 , trans, piperidinium, 1-1-cycloocten-1-ylmethyl-4-2,7-dichloro-9h-xanthen-9-yl carbonyl amino-1-ethyl-, iodide, cis, piperidinium, 1-1-cycloocten-1-ylmethyl-4-2,7-dichloro-9h-xanthen-9-yl carbonyl amino-1-ethyl-, iodide, trans, unii-e32u2esr7j component foafbmysxigaox-kekkvsgzsa-n, unii-e32u2esr7j component foafbmysxigaox-mumzcososa-n
PubChem CID 6918496
IUPAC-Name 1-[(cyclooct-1-en-1-yl)methyl]-4-(2,7-dichloro-9H-xanthene-9-amido)-1-ethylpiperidin-1-ium iodide
SMILES [I-].CC[N+]1(CC2=CCCCCCC2)CCC(CC1)NC(=O)C1C2=C(OC3=C1C=C(Cl)C=C3)C=CC(Cl)=C2

Spezifikation

Chemischer Name oder Material UCB 35625
Menge 1 mg
Formelmasse 655.44
Reinheit (%) >98%
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