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  8. Tris-(2-Carboxyethyl)phosphinhydrochlorid, 95 %, 0.5 m Lösg. in Wasser, Thermo Scientific Chemicals

Tris-(2-Carboxyethyl)phosphinhydrochlorid, 95 %, 0.5 m Lösg. in Wasser, Thermo Scientific Chemicals

Artikelnummer. 15429365
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Menge:
5 mL
25 mL
100 mL

Description

Tris(2-carboxyethyl)phosphine hydrochloride is widely used as a reducing agent to reduce disulfide bonds in proteins and trans-4,5-dihydroxy-1,2-dithiane. It is involved in the reduction of sulfoxides, sulfonyl chlorides, N-oxides and azides. It plays an important role in the tissue homogenization process for RNA isolation. It acts as a chelating agent and forms complexes with various heavy metal ions such as Zn(II), Cd(II), Pb(II), and Ni(II). Furthermore, it is useful in the labeling of cysteine residues with maleimides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Anwendungen
Tris(2-carboxyethyl)phosphin-Hydrochlorid wird häufig als Reduktionsmittel verwendet, um Disulfid-Bindungen in Proteinen und trans-4,5-dihydroxy-1,2-dithian zu reduzieren. Es ist an der Reduktion von Sulfoxiden, Sulfonylchloriden, N-Oxiden und Aziden beteiligt. Es spielt eine wichtige Rolle beim Gewebehomogenisierungsprozess für die RNA-Isolierung. Es fungiert als Chelatbildner und bildet Komplexe mit verschiedenen Schwermetallionen wie Zn(II), Cd(II), Pb(II) und Ni(II). Darüber hinaus ist es nützlich bei der Markierung von Cystein-Rückständen mit Maleimiden.

Löslichkeit
Mischbar mit Wasser und Methanol.

Hinweise
Luftempfindlich. Kühl lagern. Nicht kompatibel mit starken Oxidationsmitteln
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 51805-45-9
Summenformel C9H12O6P
Molekulargewicht (g/mol) 247.16
MDL-Nummer MFCD00145469
InChI-Schlüssel PZBFGYYEXUXCOF-UHFFFAOYSA-K
Synonym tris 2-carboxyethyl phosphine hydrochloride, tcep hcl, tcep hydrochloride, 3,3',3-phosphinetriyltripropanoic acid hydrochloride, tcep, unii-h49aam893k, tris carboxyethyl phosphine hydrochloride, tris-2-carboxyethyl phosphine hydrochloride, tris 2-carboxyethyl phosphine hcl, 3,3',3-phosphinetriyltripropanoicacidhydrochloride
PubChem CID 2734570
IUPAC-Name 3-[bis(2-carboxylatoethyl)phosphanyl]propanoate
SMILES [O-]C(=O)CCP(CCC([O-])=O)CCC([O-])=O

Specifications

Chemischer Name oder Material Tris(2-carboxyethyl)phosphine hydrochloride
Strukturformel (HO2CCH2CH2)3P·HCl
Menge 5 mL
UN-Nummer UN3265
Löslichkeitsinformationen Miscible with water and methanol.
Formelmasse 286.65
Reinheit (%) 95%
Concentration or Composition (by Analyte or Components) 0,5 M lösl. in Wasser

RUO – Research Use Only

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