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SR 2211, Tocris Bioscience™

Artikelnummer. 30002061
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Menge:
10 mg
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Beschreibung

Selective RORγ inverse agonist

Selective inverse agonist of retinoic acid receptor-related orphan receptor γ (RORγ) (Ki = 105 nM; IC50 ∽320 nM). Exhibits weak activity at liver X receptor α (LXRα); does not affect the transcriptional activity of farnesoid X receptors (FXR), and has no impact on the transcriptional activity of RORα.

Chemische Identifikatoren

CAS 1359164-11-6
Summenformel C26H24F7N3O
Molekulargewicht (g/mol) 527.487
InChI-Schlüssel KVHKWAZUPPBMLL-UHFFFAOYSA-N
Synonym 2-fluoro-4'-4-4-pyridinylmethyl-1-piperazinyl methyl-, a,, a-bis trifluoromethyl-1,1'-biphenyl-4-methanol, 1,1,1,3,3,3-hexafluoro-2-2-fluoro-4'-4-pyridin-4-ylmethyl piperazin-1-yl methyl-1,1'-biphenyl-4-yl propan-2-ol, 2-fluoro-4'-4-4-pyridinylmethyl-1-piperazinyl methyl-a,a-bis trifluoromethyl-1,1'-biphenyl-4-methanol
PubChem CID 51035449
IUPAC-Name 1,1,1,3,3,3-hexafluoro-2-[3-fluoro-4-[4-[[4-(pyridin-4-ylmethyl)piperazin-1-yl]methyl]phenyl]phenyl]propan-2-ol
SMILES C1CN(CCN1CC2=CC=C(C=C2)C3=C(C=C(C=C3)C(C(F)(F)F)(C(F)(F)F)O)F)CC4=CC=NC=C4

Spezifikation

Chemischer Name oder Material SR 2211
Menge 10 mg
Formelmasse 527.48
Reinheit (%) >98%
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