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  7. Spermidin, 99 %, Thermo Scientific Chemicals

Spermidin, 99 %, Thermo Scientific Chemicals

Artikelnummer. 11449396
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Menge:
1 g
5 g
25 g
100 g

Description

Binds to the polyamine modulatory site of NMDA Spermidine is used in electroporation during transferring the DNA into the cell under the electrical impulse. It is also used for purification of DNA-binding proteins. It combines with calcium chloride and utilized for the precipitation of DNA onto microprojectiles for bombardment with a gene gun. It plays an important role to reduce the amount of aging in yeast, flies, worms, and human immune cells by inducing autophagy. It serves as a precursor of spermine and essential for both normal and neoplastic tissue growth.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Anwendungen
Bindet an die polyaminmodulierende Stelle von NMDA Spermidin wird bei der Elektroporation während der Übertragung der DNA in die Zelle unter dem elektrischen Impuls verwendet. Es wird auch zur Reinigung von DNA-bindenden Proteinen verwendet. Es kombiniert sich mit Calciumchlorid und wird für die Präzipitation von DNA auf Mikroprojektile zum Beschuss mit einer Genkanone verwendet. Es spielt eine wichtige Rolle, um die Alterung von Hefe, Fliegen, Würmern und menschlichen Immunzellen durch die Induktion von Autophagie zu reduzieren. Es dient als Vorläufer des Spermas und ist für das normale und neoplastische Gewebewachstum unerlässlich.

Löslichkeit
Mischbar mit Wasser, Ethanol und Äther.

Hinweise
Hygroskopisch. Nicht kompatibel mit Säuren, sauren Chloriden, sauren Anhydriden und Oxidationsmitteln.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 124-20-9
Summenformel C7H19N3
Molekulargewicht (g/mol) 145.25
MDL-Nummer MFCD00008229
InChI-Schlüssel ATHGHQPFGPMSJY-UHFFFAOYSA-N
Synonym spermidine, 1,5,10-triazadecane, 4-azaoctamethylenediamine, spermidin, 4-azaoctane-1,8-diamine, n1-3-aminopropyl butane-1,4-diamine, 1,4-butanediamine, n-3-aminopropyl, n-3-aminopropyl butane-1,4-diamine, n-3-aminopropyl-1,4-butane-diamine, 1,4-diaminobutane, n-3-aminopropyl
PubChem CID 1102
ChEBI CHEBI:16610
IUPAC-Name N'-(3-Aminopropyl)butan-1,4-diamin
SMILES NCCCCNCCCN

Specifications

Chemischer Name oder Material Spermidine
Schmelzpunkt 22°C to 25°C
Dichte 0.925
Siedepunkt 128°C to 130°C (14 mmHg)
Flammpunkt >110°C (230°F)
Brechungsindex 1.479
Menge 5 g
UN-Nummer UN2735
Beilstein 1698591
Empfindlichkeit Air sensitive
Merck Index 14,8742
Löslichkeitsinformationen Miscible with water,ethanol and ether.
Formelmasse 145.25
Reinheit (%) 99%
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RUO – Research Use Only

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