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R&D Systems™ Recombinant Mouse Integrin alpha 4 beta 7 Protein
Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.
Marke: R&D Systems™ 8615-A3-050
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Beschreibung
The Recombinant Mouse Integrin alpha 4 beta 7 Protein is derived from CHO. The Recombinant Mouse Integrin alpha 4 beta 7 Protein has been validated for the following applications: Bioactivity.Spezifikation
| Bioactivity | |
| Observed M.W.: 115 - 170kDa, reducing conditions, Theoretical M.W.: 113kDa (Integrin alpha 4), 84kDa (Integrin beta 7) | |
| Chinese Hamster Ovary cell line,CHO-derived mouse Integrin alpha 4 beta 7/LPAM-1 protein, (N-terminus) Mouse Integrin alpha 4 Tyr34-Gln970 (Arg591Leu) Accession &Num; AAH68313 GS Linker Acidic Tail HHHHHH Mouse Integrin ss7 Glu20-Arg724 Accession &Num; P26011 GS Linker Basic Tail (C-terminus) | |
| <0.10 EU per 1μg of the protein by the LAL method. | |
| Integrin alpha 4 beta 7/LPAM-1 | |
| Measured by the ability of the immobilized protein to support the adhesion of CHO Chinese hamster ovary cells transfected with VCAM-1. The ED50 for this effect is typically 0.6-3.6μg/mL. | |
| Mouse | |
| Chinese Hamster Ovary cell line, CHO-derived Mouse Integrin alpha 4 Tyr34-Gln970 (Arg591Leu) Accession # AAH68313, GS Linker, Acidic Tail, N-terminus; HHHHHH; Mouse Integrin ss7 Glu20-Arg724 Accession # P26011, GS Linker Basic Tail, C-terminus |
| 3676 | |
| 50 μg | |
| Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70° C as supplied. 1 month, 2 to 8° C under sterile conditions after reconstitution. 3 months, -20 to -70° C under sterile conditions after reconstitution. | |
| 269C wild type, CD49 antigen-like family member D, CD49d, CD49d antigen, CD49d/beta7, CD49Dantigen CD49D, alpha-4 subunit of VLA-4 receptor, IA4, integrin alpha 4, integrin alpha-4, integrin alpha-4 subunit, Integrin alpha-IV, integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor), LPAM1, LPAM-1, MGC90518, very late activation protein 4 receptor, alpha 4 subunit, VLA-4 subunit alpha | |
| Itga5 | |
| Unconjugated | |
| Recombinant | |
| >95%, by SDS-PAGE with Silver Staining |
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