missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemikalien
  4. Organische Verbindungen
  5. Benzoide
  6. Benzol und substituierte Derivate
  7. Acylaminobenzoesäure und Derivate
  8. 18055582

PYR 41, Tocris Bioscience™

Artikelnummer. 18055582
Click to view available options
10mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Ubiquitin-activating enzyme (E1) inhibitor

Cell-permeable, irreversible ubiquitin-activating enzyme (E1) inhibitor (IC50 < 10 μM). Blocks ubiquitination and prevents ubiquitin-mediated proteasomal degradation. Inhibits NF-κB activation, blocks degradation of p53, increases p21 levels and induces apoptosis in vitro. Also causes an increase in sumoylation of proteins.

Specifications

Chemischer Name oder Material PYR 41
CAS 418805-02-4
Summenformel C17H13N3O7
Menge 10 mg
Synonym pyr-41, pyr 41, pyr41, ubiquitin e1 inhibitor, pyr-41, ethyl 4-4z-4-5-nitrofuran-2-yl methylidene-3,5-dioxopyrazolidin-1-yl benzoate, benzoic acid, 4-4-5-nitro-2-furanyl methylene-3,5-dioxo-1-pyrazolidinyl-, ethyl ester, 4-4-5-nitro-furan-2-ylmethylene-3,5-dioxo-pyrazolidin-1-yl-benzoic acid ethyl ester, 4 4-5-nitro-furan-2-ylmethylene-3,5-dioxo-pyrazolidin-1-yl-benzoic acid ethyl ester
InChI-Schlüssel ARGIPZKQJGFSGQ-LCYFTJDESA-N
SMILES CCOC(=O)C1=CC=C(C=C1)N2C(=O)C(=CC3=CC=C(O3)[N+](=O)[O-])C(=O)N2
IUPAC-Name ethyl 4-[(4Z)-4-[(5-nitrofuran-2-yl)methylidene]-3,5-dioxopyrazolidin-1-yl]benzoate
Molekulargewicht (g/mol) 371.305
PubChem CID 5335621
Formelmasse 371.3
Reinheit (%) >98%
Show More Show Less
missing translation for 'provideContentCorrection'

missing translation for 'productTitle'

missing translation for 'byClickingSubmit' missing translation for 'privacyPolicy'.