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Novus Biologicals™ Pam3CSK4, TLR1 and TLR2 Ligand

Applications: Functional, In vitro assay, In vivo assay, Ligand Activation

272.00 CHF - 273.00 CHF

Spezifikation

Konzentration 0.5 mg/mL
Inhalt und Lagerung Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Zur Verwendung mit (Anwendung) Activation of TLR1 and TLR2 heterodimer. Stimulation of TLR1 and TLR2 has been reported with 10 to 100ng/mL. Use in vitro assay reported in scientific literature (PMID: 24105263) Use in functional reported in scientific literature (PMID 25511699). Use in In-vivo reported in scientific literature (PMID 25466255). Use in ligand activation reported in multiple pieces scientific literature.
Ziel Pam3CSK4, TLR1 and TLR2 Ligand
Spezies Human/Mouse
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Produkte 2
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
18705143
Unterlagen ansehen
Novus Biologicals™
NBP2-25297-0.025mg
0.025 mg
272.00 CHF
25 Mikrogramm
Verfügbar ab: 09-12-2024
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18796653
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Novus Biologicals™
0.1 mg
273.00 CHF
0.10 Milligramm
Verfügbar ab: 09-12-2024
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Beschreibung

Beschreibung

Pam3CSK4, TLR1 and TLR2 Ligand is a synthetic tripalmitoylated lipohexapeptide analog of the immunologically active N-terminal portion of bacterial lipoprotein. It activates monocytes and macrophages and is also a potent activator of proinflammatory transcription factor NF-kB. Pam3CSK4, TLR1 and TLR2 Ligand is recognized by a heterodimer formed between TLR1 and TLR2. Pam3CSK4, TLR1 and TLR2 Ligand stimulation: If your cell line does not naturally express TLR1+ TLR2, co-transfect with plasmids pCMV/TLR1and pCMV/TLR2. Forty-eight hours after transfection, stimulate cells with 10 to 100ng/ml of Pam3CSK4 for 6 to 24 hours. Determine Pam3CSK4 stimulation using appropriate detection assays. Buffer: Sterile water
Spezifikation

Spezifikation

0.5 mg/mL
Activation of TLR1 and TLR2 heterodimer. Stimulation of TLR1 and TLR2 has been reported with 10 to 100ng/mL. Use in vitro assay reported in scientific literature (PMID: 24105263) Use in functional reported in scientific literature (PMID 25511699). Use in In-vivo reported in scientific literature (PMID 25466255). Use in ligand activation reported in multiple pieces scientific literature.
Human/Mouse
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Pam3CSK4, TLR1 and TLR2 Ligand
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