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p65/RELA Rabbit anti-Human, Mouse, Porcine, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marke: Proteintech 10745-1-AP-150UL
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Description
This antibody is a rabbit polyclonal antibody raised against residues near the N terminus of human RELA.
The transcription factor NFkB is widely recognized as a critical mediator of immune and inflammatory responses. In most cell types, NFkB is found in the cytoplasm where it is associated with an inhibitory protein known as IkB. An impressive variety of stimuli (tumor necrosis factor, interleukin 1, T-cell activation signals, bacterial endotoxins, viral transforming proteins, certain growth factors and reactive oxygen intermediates) lead to the rapid nuclear assumulation of NFkB by the induced phosphorylation and subsquent degradation of IkB. In the nucleus, NFkB regulates genes encoding cytokines, cytokine receptors, cell adhesion molecules, proteins involved in coagulation and genes involved in cell growth control. Additionally, NFkB is thought to be an important transcriptional regulator for HIV. Growing evidence indicates that the dysregulation of NFkB may be key to a number of diseases including arthritis and other inflammatory diseases, Alzheimer′s disease, atherosclerosis, and cancer.Spécification
p65/RELA | |
Polyclonal | |
Unconjugated | |
RELA | |
NFKB 3, NFKB p65, NFKB3, p65, RELA, Transcription factor p65 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
100135665, 19697, 309165, 5970 | |
-20°C | |
Liquid |
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation | |
0.52 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
Q04206, Q04207 | |
RELA | |
p65; RELA Fusion Protein Ag1199 | |
150 μL | |
Primary | |
Human, Mouse, Porcine, Rat | |
Antibody | |
IgG |
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Nom du produit
p65/RELA Rabbit anti-Human, Mouse, Porcine, Rat, Polyclonal, Proteintech > 150 μL; Unconjugated
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