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NF 279, Tocris Bioscience™

Artikelnummer. 18044362
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Menge:
10 mg
50 mg
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Potent and selective P2X1 antagonist

NF 279 is a a potent and selective P2X1 antagonist (IC50 = 19 nM). Displays good selectivity over P2X2,(IC50 = 0.76 μM), P2X3 (IC50 = 1.62μM), P2X4 (IC50 > 300 μM), P2Y receptors and ecto-nucleotidases.

This product is supplied with a high degree of hydration and some residual NaCl, the amount of which are batch dependent. Please refer to the Certificate of Analysis to obtain the batch specific Net Product Content.

Chemische Identifikatoren

CAS 202983-32-2
Summenformel C49H36N6Na6O23S6
Molekulargewicht (g/mol) 1407.145
InChI-Schlüssel RRKORSRLXJQAGK-UHFFFAOYSA-N
Synonym 8,8'-[Carbonylbis(imino-4,1-phenylenecarbonylimino-4,1-phenylenecarbonylimino)]bis-1,3,5-naphthalenetrisulfonic acid hexasodium salt
PubChem CID 131850945
IUPAC-Name sodium;8-[[4-[[4-[[4-[[4-[(4,6,8-trisulfonaphthalen-1-yl)carbamoyl]phenyl]carbamoyl]phenyl]carbamoylamino]benzoyl]amino]benzoyl]amino]naphthalene-1,3,5-trisulfonic acid
SMILES C1=CC(=CC=C1C(=O)NC2=C3C(=CC(=CC3=C(C=C2)S(=O)(=O)O)S(=O)(=O)O)S(=O)(=O)O)NC(=O)C4=CC=C(C=C4)NC(=O)NC5=CC=C(C=C5)C(=O)NC6=CC=C(C=C6)C(=O)NC7=C8C(=CC(=CC8=C(C=C7)S(=O)(=O)O)S(=O)(=O)O)S(=O)(=O)O.[Na].[Na].[Na].[Na].[Na].[Na]

Spezifikation

Chemischer Name oder Material NF 279
Menge 10 mg
Formelmasse 1401.1
Reinheit (%) >98%
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