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Invitrogen™ Human MLK4, GST Tag Recombinant Protein
This MLK4 Recombinant Human Protein (114-420) was expressed in insect cells.
Marke: Invitrogen™ A33382
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Beschreibung
MLK4 or mixed lineage kinase 4 belongs to the superfamily of MAP kinase kinase kinases (MAP3K1) which contain both ser/thr and tyr kinases activity in their catalytic domains. The structure of this kinase family incorporates an N-terminal Src homology (SH3) domain, followed by the kinase domain, a leucine zipper region, and a CDC42 /RAC -interactive binding (CRIB) motif, but divergent C-terminal regions. MLK4 is highly expressed in the kidney and pancreas. MLK4 is a negative regulator of TLR4.- Validated for use with the LanthaScreen™ Eu Kinase Binding assay
- Available in multiple pack sizes for convenient use
Spezifikation
| NP_115811 | |
| 60.5 kDa | |
| MAP Kinases | |
| Human | |
| GST Tag | |
| Dry Ice | |
| Recombinant, Active, Catalytic |
| Kinase Assay | |
| 1 mg | |
| aa 114 - 420 | |
| Recombinant | |
| Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. | |
| Insect | |
| Liquid |