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Mirtazapine, Tocris Bioscience™

Artikelnummer. 30001439
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Menge:
10 mg
50 mg
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Beschreibung

Potent 5-HT2 antagonist; also 5-HT3, H1 and α2 antagonist; antidepressant

Mirtazapine is an antidepressant agent; potent 5-HT2, 5-HT3 and histamine H1 receptor antagonist and moderately potent α2-adrenoceptor antagonist (pKi values are 8.05, ∼ 8.1, 9.3 and 6.95 respectively). Enhances noradrenaline (NA) release in rat brain via inhibition of α2-adrenergic autoreceptors and displays only weak affinity for monoamine transporters (pKi values are 5.6, < 5 and < 5.1 for inhibition of NA, dopamine and 5-HT uptake respectively). Increases hippocampal NA and 5-HT levels in rats following systemic administration in vivo.

Chemische Identifikatoren

CAS 85650-52-8
Summenformel C17H19N3
Molekulargewicht (g/mol) 265.36
InChI-Schlüssel RONZAEMNMFQXRA-UHFFFAOYSA-N
Synonym mirtazapine, remeron, mepirzepine, remergil, zispin, remergon, rexer, 6-azamianserin, remeron soltab, mepirzapin
PubChem CID 4205
ChEBI CHEBI:6950
SMILES CN1CCN2C(C1)C3=CC=CC=C3CC4=C2N=CC=C4

Spezifikation

Chemischer Name oder Material Mirtazapine
Menge 10 mg
Formelmasse 265.36
Reinheit (%) >99%
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