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Invitrogen™ Human MET (cMET) [Y1235D], GST Tag Recombinant Protein
Human MET (cMET) [Y1235D], GST Tag Recombinant Protein
Marke: Invitrogen™ A33505
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Beschreibung
- This MET (cMET) Y1235D recombinant human protein (956-end) was expressed in insect cells
- MET receptor tyrosine kinase is a proto-oncogene that encodes a transmembrane growth factor receptor
- MET is widely expressed in the kidney, brain, lung, skin, and embryonic tissue
- Hepatocyte growth factor (HGF) binds to MET and activates its tyrosine kinase activity
- MET is overexpressed and activated in a variety of human cancers including pancreatic, colon, gastric, cervical and ovarian cancers
- It has also been shown to be involved in tumor cell migration and invasion
- MET (Y1235D) is one of the native mutant forms of MET
- MET (cMET) Y1235D recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service
- Validated for use with the Z'-LYTE™ assay
- Available in multiple pack sizes for convenient use
Spezifikation
NP_000236.2 | |
75.4 kDa | |
METs (HGFRs) | |
Human | |
GST Tag | |
Dry Ice | |
Kinases & Inhibitors | |
Liquid |
Kinase Assay | |
10 μg | |
aa 956 - 1390 | |
Recombinant | |
Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol | |
Baculovirus | |
Recombinant, Active, Cytoplasmic, Mutant |
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