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Kenpaullone, Tocris Bioscience™
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Menge:
10 mg
Beschreibung
GSK-3beta inhibitor (IC50 = 0.23 μM). Also inhibits cyclin dependent kinases (cdks) in the sub micromolar range (reported IC50 values are 0.4, 0.68-7 and 0.85 μM for cdk1, cdk2 and cdk5, respectively). Generates induced pluripotent stem cells (iPSCs) from somatic cells when used in combination with reprogramming factors; can replace Klf4.
Spezifikation
Spezifikation
Chemischer Name oder Material | Kenpaullone |
CAS | 142273-20-9 |
Summenformel | C16H11BrN2O |
Menge | 10 mg |
Synonym | kenpaullone, 9-bromopaullone, 9-bromo-7,12-dihydroindolo 3,2-d 1 benzazepin-6 5h-one, indolo 3,2-d 1 benzazepin-6 5h-one,9-bromo-7,12-dihydro, 9-bromo-7,12-dihydro-indolo 3,2-d 1 benzazepin-6 5h-one, 9-bromo-7,12-dihydro-5h-indolo 3,2-d 1 benzazepin-6-one, 9-bromo-7,12-dihydro-indolo-3,2-d-1 benzazepin-6 5h-one, 9-bromo-7,12-dihydrobenzo 2,3 azepino 4,5-b indol-6 5h-one, indolo 3,2-d 1 benzazepin-6 5h-one, 9-bromo-7,12-dihydro |
InChI-Schlüssel | QQUXFYAWXPMDOE-UHFFFAOYSA-N |
SMILES | C1C2=C(C3=CC=CC=C3NC1=O)NC4=C2C=C(C=C4)Br |
IUPAC-Name | 9-bromo-7,12-dihydro-5H-indolo[3,2-d][1]benzazepin-6-one |
Molekulargewicht (g/mol) | 327.181 |
PubChem CID | 3820 |
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