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Invitrogen™ Human IRAK3, GST Tag Recombinant Protein
This IRAK3 Recombinant Human Protein (full length) was expressed in insect cells.
Marke: Invitrogen™ A32893
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Beschreibung
- This IRAK3 recombinant human protein (full length) was expressed in insect cells
- IRAK3 serine/threonine kinase, or interleukin-1 receptor-associated kinase 3, is a member of the interleukin-1 receptor-associated kinase protein family
- This family is resposible for essential components of the Toll/IL-R immune signal transduction pathways
- IRAK3 is primarily expressed in monocytes and macrophages
- It functions as a negative regulator of Toll-like receptor signaling
- IRAK3 mediates critical aspects of innate immunity that result in an immunocompromised state during sepsis
- Mutations in IRAK3 are associated with a susceptibility to asthma
- IRAK3 recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service
- Validated for use with the LanthaScreen™ Eu Kinase Binding assay
- Available in multiple pack sizes for convenient use
Spezifikation
AAH57800 | |
94.0 kDa | |
IRAK Kinase Family | |
Human | |
GST Tag | |
Dry Ice | |
Kinases & Inhibitors | |
Liquid |
Kinase Assay | |
100 μg | |
Full Length | |
Recombinant | |
Storage Buffer: 50 mM Tris-HCl, pH 7.5, 50 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol | |
Baculovirus | |
Recombinant, Full Length |