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Tocris Bioscience™ I-BET 762

Potent and high affinity BET bromodomain inhibitor; anti-inflammatory; orally bioavailable.

154.00 CHF - 517.00 CHF

Specifications

Chemischer Name oder Material (4S)-6-(4-Chlorophenyl)-N-ethyl-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine-4-acetamide
CAS 1260907-17-2
Ziel Bromodomain Inhibitors
Summenformel C22H22ClN5O2
Reinheit 0.98
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Products 2
Product Code Brand Menge Price Quantity & Availability  
Product Code Brand Menge Price Quantity & Availability  
18094322
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Tocris Bioscience™
6521/25
25 mg
517.00 CHF
25 Milligramm
Verfügbar ab: 29-01-2025
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18054232
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Tocris Bioscience™
6521/5
5 mg
154.00 CHF
5 Milligramm
Verfügbar ab: 29-01-2025
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Description

Description

I-BET 762 is a potent and high affinity BET bromodomain inhibitor (IC50 = 32.5 - 42.5 nM; Kd = 50.5 - 61.3 nM). Inhibits myeloma cell proliferation. Attenuates transcription of oncogenic MYC and suppresses key inflammatory genes. Exhibits efficacy in a range of oncology and immunoinflammatory models. Displays antiproliferative effect in vitro and in vivo. Orally bioavailable.
Specifications

Specifications

(4S)-6-(4-Chlorophenyl)-N-ethyl-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine-4-acetamide
Bromodomain Inhibitors
0.98
1260907-17-2
C22H22ClN5O2
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Safety and Handling

Safety and Handling

Recommended Storage : Lagerung bei -20 °C

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