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Gibco™ Human Noggin Recombinant Protein, PeproTech®
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Menge:
100 μg
2 x 500 μg
20 μg
250 μg
5 μg
50 μg
500 μg
Packungsgröße:
1 Milligramm
100 Mikrogramm
2 Stück
20 Mikrogramm
250 Mikrogramm
5 Mikrogramm
50 Mikrogramm
500 Mikrogramm
Beschreibung
120-10C-1MG will be provided as 2 x 500 μg (120-10C-500UG). Recombinant Human Noggin is a 46 kDa disulfide-linked homodimer consisting of two 205 amino acid polypeptide chains. Monomeric glycosylated noggin migrates at an apparent molecular weight of approximately 28.0-33.0 kDa by SDS PAGE analysis under reducing conditions. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation. The morphogenesis of organs is initiated by a downgrowth from a layer of epithelial stem cells. This process is achieved through the receipt of signals from 1) a WNT protein (WNT3A) to stabilize beta-catenin; and 2) Noggin, which is a bone morphogenetic protein inhibitor. Noggin mutations in unrelated families with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1) have been identified, which have multiple joint fusion as their principal defect.

Spezifikation
Spezifikation
Zugriffsnummer | Q13253 |
Zur Verwendung mit (Anwendung) | Functional Assay |
Zusammensetzung | protein with no preservative |
Gen-ID (Entrez) | 9241 |
Molekulargewicht | 46 kDa |
Name | Human Noggin |
Menge | 100 μg |
Quelle | HEK293 cells |
Kennzeichnung | RUO |
Endotoxin-Konzentration | <1 EU/ μg |
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