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  6. Tocris Bioscience™ FTY 720
  7. 18761508

Tocris Bioscience™ FTY 720

Potent S1P receptor agonist; also immunosuppressant

Marke:  Tocris Bioscience™ 6176/50

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Artikelnummer. 18761508

  • 588.00 CHF / 50 Milligramm
Verfügbar ab: 22-01-2025
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Description

Description

FTY 720 is an S1P receptor agonist; undergoes phosphorylation by sphingosine kinase 2, which then binds S1P1,3,4 and 5 receptors (EC50 values are 0.3 - 0.6 nM for S1P1, 4 and 5 and ∼3 nM for S1P3). Immunosuppressant; sequesters lymphocytes in lymph nodes, reducing autoimmune response. Suppresses the development of EAE (an in vivo model of MS). Orally bioavailable and blood-brain barrier permeable.
Specifications

Specifications

Agonist
162359-56-0
343.93g/mol
Store at -20°C
50 mg
Sphingosine-1-phosphate Receptor
C19H33NO2.HCl
Fingolimod, Gilenya
Sphingosine-1-phosphate Receptor Agonists
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