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ErbB2 (HER-2), His Tag ErbB2 (HER2), His Tag Recombinant Protein
ErbB2 (HER-2), His Tag ErbB2 (HER2), His Tag Recombinant Protein
Marke: Invitrogen PV3590
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Beschreibung
ErbB2 (HER2) is a receptor tyrosine kinase that is overexpressed in some breast tumors. Herceptin, used in treatment of metastatic Her2-positive cancer, is monoclonal antibody targeting this kinase.
Spezifikation
| NP_004439 | |
| Protein Assays and Analysis, Kinase Assay | |
| 68.6kDa | |
| 1 mg | |
| For research use only. Not for use in diagnostic procedures | |
| ErbB2 (HER2) | |
| EGF receptor (ErbB) | |
| ErbB2 (HER2) | |
| Human | |
| Baculovirus | |
| 60% by SDS-PAGE |
| 0.33mg/mL | |
| Frozen | |
| ERBB2 (HER2) | |
| –80°C | |
| ErbB2 (HER2), NEU | |
| ERBB2 (HER2) was pre-diluted in enzyme dilution buffer and assayed in 20mM Tris (pH 7.5), 5 MnCl2, 1mM EGTA, 0.5mM Na3VO4, 5mM β-glycerophosphate, 2mM DTT, 0.01% CHAPS, 200μM ATP, 1000μg/mL poly [Glu, Tyr] 4:1 substrate and trace [32P]-γ-ATP for 10 minutes at 30°C | |
| Amino acids 676-1255 | |
| 78nmoles of phosphate transferred to poly [Glu, Tyr] 4:1 substrate per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 8.33μg/mL | |
| His Tag | |
| Frozen |
For Research Use Only. Not for use in diagnostic procedures.