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Dynasore, Tocris Bioscience™

Artikelnummer. 18015142
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Menge:
10 mg
50 mg
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Non-competitive dynamin inhibitor

Dynasore is a non-competitive reversible inhibitor of dynamin 1, dynamin 2 and mitochondrial dynamin (Drp1) GTPase activity. Dynasore blocks endocytic pathways dependent on dynamin and inhibits cell spreading and migration of BSC1 cells. Dynasore attenuates motor symptoms in an animal model of Parkinson's disease and in a cellular model of Alzheimer's disease it reduces tau protein aggregation and internalization.

Chemische Identifikatoren

CAS 304448-55-3
Summenformel C18H14N2O4
Molekulargewicht (g/mol) 322.32
MDL-Nummer MFCD00292551
InChI-Schlüssel NRQJUIHYFNUXFT-UHFFFAOYSA-N
Synonym dynamin inhibitor i, dynasore, n'-3,4-dihydroxybenzylidene-3-hydroxy-2-naphthohydrazide, 3-hydroxy-n'-3-hydroxy-4-oxocyclohexa-2,5-dien-1-ylidene methyl naphthalene-2-carbohydrazide, dynasore monohydrate, n'-1e-3,4-dihydroxyphenyl methylidene-3-hydroxynaphthalene-2-carbohydrazide, n'-3,4-dihydroxyphenyl methylidene-3-hydroxynaphthalene-2-carbohydrazide, 2-naphthalenecarboxylicacid, 3-hydroxy-, 2-3,4-dihydroxyphenyl methylene hydrazide
PubChem CID 6739924
IUPAC-Name 3-hydroxy-N'-[(3-hydroxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]naphthalene-2-carbohydrazide
SMILES OC1=CC(=CNNC(=O)C2=CC3=CC=CC=C3C=C2O)C=CC1=O

Spezifikation

Chemischer Name oder Material Dynamin Inhibitors
Menge 10 mg
Formelmasse 322.32
Reinheit (%) >99%
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