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DPO-1, Tocris Bioscience™

Artikelnummer. 30001329
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Menge:
10 mg
50 mg
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Beschreibung

Blocker of KV1.5 channel and IKur current

Blocker of IKur ultrarapid delayed rectifier potassium current and KV1.5 channels (IC50 = 0.31 μM for rKV1.5). Displays selectivity for inhibition of IKur over Ito (8-fold), IK1, IKr and IKs (20-fold) in native myocytes and selectivity for rat recombinant KV1.5 over KV3.1 (∽ 15-fold). Increases action potential duration in atrial but not ventricular myocytes and prevents atrial arrhythmia.

Chemische Identifikatoren

CAS 43077-30-1
Summenformel C22H29OP
Molekulargewicht (g/mol) 340.45
MDL-Nummer MFCD09038567
InChI-Schlüssel BPCNGVCAHAIZEE-UHFFFAOYNA-N
Synonym dpo-1, neomenthyldiphenylphosphine oxide, +-neomenthyl diphenylphosphine oxide, 1s,2s,5r-5-methyl-2-1-methylethyl cyclohexyl diphenyl-phosphine oxide, diphenyl phosphine oxide-1, dpo-1, needles nmr, 1s,2s,5r-2-isopropyl-5-methylcyclohexyl diphenyl phosphine oxide, 1s,2s,5r-2-isopropyl-5-methylcyclohexyl phenyl phosphoroso benzene, 1s,2s,5r-5-methyl-2-propan-2-yl cyclohexyl oxo diphenyl-lambda∼5∼-phosphane, 1s-1?,2?,5?-5-methyl-2-1-methylethyl cyclohexyl diphenylphosphine oxide
PubChem CID 21678144
IUPAC-Name {[5-methyl-2-(propan-2-yl)cyclohexyl](phenyl)phosphoroso}benzene
SMILES CC(C)C1CCC(C)CC1P(=O)(C1=CC=CC=C1)C1=CC=CC=C1

Spezifikation

Chemischer Name oder Material DPO-1
Menge 10 mg
Formelmasse 340.44
Reinheit (%) >99%
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