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Thermo Scientific™ CellSensor™ ISRE-bla HEK293T Cell Line
The CellSensor™ ISRE-bla HEK 293T cell line is responsive to interferon alpha and can be used to probe the JAK/STAT signaling pathway.
Marke: Thermo Scientific™ K1655
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Beschreibung
Interferon cell signaling is a critical pathway involved in viral defense and autoimmune disease. The CellSensor™ ISRE-bla HEK 293T cell line is responsive to interferon alpha and can be used to probe the JAK/STAT signaling pathway. The CellSensor™ ISRE-bla HEK 293T cell line contains the β-lactamase reporter gene under the control of the interferon stimulated response element (ISRE). This cell line was engineered by transduction of the ISRE-bla construct into HEK 293T cells by lentivirus. Flow cytometry was then used to isolate a pool of clones responsive to interferon alpha a stimulation. A dose response curve for this assay against interferon alpha is available in the validation packet. Academic and non-profit customers, please inquire for special pricing.
Spezifikation
| Zellbasiertes Beta-Lactamase-Reportergen | |
| CellSensor™ Zelllinien werden auf Trockeneis geliefert. Sofort nach Erhalt in Flüssigstickstoff lagern oder zur sofortigen Verwendung auftauen. | |
| CellSensor™ | |
| Jak/STAT (Typ I IFN) Signalweg, TYK2, JAK1 | |
| CellSensor™ |
| Teilende Zellen | |
| Zytokine, Signalweg | |
| 1 Fläschchen | |
| Teilende Zellen | |
| Signalweg |
Nur für Forschungszwecke. Nicht zur Verwendung bei diagnostischen Verfahren.