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Bay 11-7821, Tocris Bioscience™
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Menge:
10 mg
Beschreibung
E2 ubiquitin (Ub) conjugating enzyme inhibitor. Inhibits the conjugation of Ub to a range of E2 enzymes. Inhibits E2 enzyme mediated IκBα phosphorylation and indirectly decreases NF-κb activity. Also reversibly activates MAPK signaling. Induces apoptosis of leukemic T cell and B-cell lymphoma cell lines. Also inhibits activation of NLRP3 inflammasome.
Spezifikation
Spezifikation
| Chemischer Name oder Material | Bay 11-7821 |
| CAS | 19542-67-7 |
| Summenformel | C10H9NO2S |
| MDL-Nummer | MFCD00712162 |
| Menge | 10 mg |
| Synonym | e-3-tosylacrylonitrile, e-3-p-toluenesulfonyl acrylonitrile, unii-4y5g2a4f6o, e-3-4-methylphenyl sulfonylprop-2-enenitrile, 3-p-toluenesulfonyl acrylonitrile, e, 3-4-methylphenylsulfonyl-2-propenenitrile, e-3-4-methylphenylsulfonyl-2-propenenitrile, e 3-4-methylphenyl sulfonyl-2-propenenitrile, 2e-3-4-methylphenyl sulfonyl prop-2-enenitrile, 2-propenenitrile, 3-4-methylphenyl sulfonyl-, 2e |
| InChI-Schlüssel | DOEWDSDBFRHVAP-KRXBUXKQSA-N |
| SMILES | CC1=CC=C(C=C1)S(=O)(=O)\C=C\C#N |
| IUPAC-Name | (2E)-3-(4-methylbenzenesulfonyl)prop-2-enenitrile |
| Molekulargewicht (g/mol) | 207.25 |
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