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Tocris Bioscience™ AZD 8055
Highly potent and selective mTOR inhibitor
Marke: Tocris Bioscience™ 7840/10
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Beschreibung
AZD 8055 is a highly potent, selective and ATP-competitive mTOR inhibitor (IC50 = 0.8 nM). Inhibits growth and induces autophagy in a range of cancer cell lines and xenografts, including NSCLC and glioblastoma (IC50 values are 20, 50 and 53 nM in H838, A549 and U87MG cell lines, respectively). Orally bioavailable.Spezifikation
| 5-[2,4-Bis[(3S)-3-methyl-4-morpholinyl]pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol | |
| 10 mg | |
| C25H31N5O4 |
| 1009298-09-2 | |
| mTOR Inhibitors | |
| 0.98 |