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5,7-Dihydroxy-4'-Methoxyisoflavon, 98 %, Thermo Scientific Chemicals

Artikelnummer. 11330528
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Menge:
250 mg
1 g
5 g
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Dieser Artikel kann nicht zurückgegeben werden. Rückgaberichtlinie anzeigen

It has putative benefits in dietary cancer prophylaxis. It has also been found to inhibit fatty acid amide hydrolase and to act as agonist of PPARgamma, nuclear receptor that is current pharmacological target for the treatment of diabetes type 2. It acts as an antineoplastic agent. It is a selective agonist at ER-β estrogen receptors, and may have chemopreventive efficacy against breast cancer. In line with its low activity at ER-α estrogen receptors, it is essentially devoid of uterotrophic activity. Biochanin A is also a ligand for the aryl hydrocarbon receptor (AhR). It reduces arterial resistance and enhances microcirculation perhaps via effects on potassium and/or calcium ion channels. Induction of sulfotransferases for xenobiotic detoxification has been proposed as a mechanism of its cancer preventive effects. It is a nitric oxide synthase inhibitor and apoptosis inducer

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

TRUSTED_SUSTAINABILITY

Chemische Identifikatoren

CAS 491-80-5
Summenformel C16H12O5
Molekulargewicht (g/mol) 284.27
MDL-Nummer MFCD00006839
InChI-Schlüssel WUADCCWRTIWANL-UHFFFAOYSA-N
Synonym biochanin a, biochanin, 4'-methylgenistein, 5,7-dihydroxy-4'-methoxyisoflavone, 5,7-dihydroxy-3-4-methoxyphenyl-4h-chromen-4-one, genistein 4-methyl ether, pratensol, biochanine a, 5,7-dihydrox-4'-methoxyisoflavone, 4h-1-benzopyran-4-one, 5,7-dihydroxy-3-4-methoxyphenyl
PubChem CID 5280373
ChEBI CHEBI:17574
IUPAC-Name 5,7-dihydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one
SMILES COC1=CC=C(C=C1)C1=COC2=CC(O)=CC(O)=C2C1=O

Specifications

Chemischer Name oder Material 5,7-Dihydroxy-4'-methoxyisoflavone
Schmelzpunkt 210°C to 213°C
Menge 5 g
Beilstein 278107
Löslichkeitsinformationen Soluble in water (<1mg/ml at 25°C),chloroform,methanol,DMSO (57mg/ml at 25°C),and ethanol (9mg/ml at 25°C).
Formelmasse 284.27
Reinheit (%) 98%
Physikalische Form Pulver

RUO – Research Use Only

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