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Xanthohumol, Tocris Bioscience™
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Menge:
10 mg
Beschreibung
p97 ATPase (VCP) inhibitor. Binds to the N domain of p97, impairing autophagosome function and maturation. Inhibits proliferation and induces apoptosis in a variety of human cancer cell lines. Also inhibits DGAT in rat liver microsomes (IC50 = 50.3 μM).
Spezifikation
Spezifikation
| Chemischer Name oder Material | Xanthohumol |
| CAS | 6754-58-1 |
| Summenformel | C21H22O5 |
| Menge | 10 mg |
| Synonym | xanthohumol, 1-2,4-dihydroxy-6-methoxy-3-3-methylbut-2-en-1-yl phenyl-3-4-hydroxyphenyl prop-2-en-1-one, unii-t4467yt1nt, 2',4,4'-trihydroxy-6'-methoxy-3'-prenylchalcone, 1-2,4-dihydroxy-6-methoxy-3-3-methyl-2-butenyl phenyl-3-4-hydroxyphenyl-2-propen-1-one, 2e-1-2,4-dihydroxy-6-methoxy-3-3-methylbut-2-en-1-yl phenyl-3-4-hydroxyphenyl prop-2-en-1-one, e-1-2,4-dihydroxy-6-methoxy-3-3-methyl-2-butenyl phenyl-3-4-hydroxyphenyl propenone, e-1-2,4-dihydroxy-6-methoxy-3-3-methylbut-2-enyl phenyl-3-4-hydroxyphenyl prop-2-en-1-one, xanthohumol from hop humulus lupulus, 2',4,4'-trihydroxy-3'-prenyl-6'-methoxychalcone |
| InChI-Schlüssel | ORXQGKIUCDPEAJ-YRNVUSSQSA-N |
| SMILES | CC(=CCC1=C(C=C(C(=C1O)C(=O)C=CC2=CC=C(C=C2)O)OC)O)C |
| IUPAC-Name | (E)-1-[2,4-dihydroxy-6-methoxy-3-(3-methylbut-2-enyl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one |
| Molekulargewicht (g/mol) | 354.402 |
| PubChem CID | 639665 |
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