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TIM-4 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Marke:  Thermo Scientific PA5116045

Artikelnummer. 17278823

  • 490.00 CHF / 100 Mikroliter
Verfügbar ab: 15-01-2025
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Beschreibung

Beschreibung

Antibody detects endogenous levels of total TIM 4.

The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors that are involved in the regulation of T helper (Th) -1 and -2 cell-mediated immunity. TIM-4, which is preferentially expressed on macrophages and dendritic cells, is the natural ligand of TIM-1, and this binding leads to T-cell expansion and cytokine production. Unlike other members of the TIM family, TIM-4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain. The TIM-4 gene maps to a locus associated with predisposition to asthma in both mice and humans and with its connection to TIM-1-triggered Th2 responsiveness, may be considered as a candidate disease/predisposition gene for asthma.
TRUSTED_SUSTAINABILITY
Spezifikation

Spezifikation

TIM-4
Polyclonal
Unconjugated
TIMD4
B430010N18Rik; RGD1564516; smuckler; soluble TIM 4; Spleen, mucin-containing, knockout of lymphotoxin protein; sTIM 4; T cell immunoglobulin and mucin domain containing 4; T-cell immunoglobulin and mucin domain containing 4; T-cell immunoglobulin and mucin domain-containing protein 4; T-cell immunoglobulin mucin receptor 4; T-cell membrane protein 4; Tim4; TIM-4; TIMD4; TIMD-4
Rabbit
Affinity chromatography
RUO
276891, 497891, 91937
-20°C
Liquid
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide
Q6U7R4, Q96H15
TIMD4
A synthesized peptide derived from human TIMD4(Accession Q96H15), corresponding to amino acid residues S272-S322.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
Produktvorschläge

Produktvorschläge

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Dokumentation

Dokumentation

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