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Thermo Scientific™ Tango™ GPR44 (CRTH2)-bla U2OS Cells
Tango™ GPR44-bla U2OS cells contain the human G protein coupled receptor 44 (GPR44) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Marke: Thermo Scientific™ K1859
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Beschreibung
Tango™ GPR44-bla U2OS cells contain the human G protein coupled receptor 44 (GPR44) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase reporter gene under the control of a UAS response element. The Tango™ GPR44-bla U2OS cells have been functionally validated for Z' factor and EC50 concentrations of Indomethacin. In addition, Tango™ GPR44-bla U2OS cells have been tested for assay performance under variable conditions.
Spezifikation
| NM_004778 | |
| Teilende Zellen | |
| Schwanz von GRPR GPCR | |
| FRET | |
| Auf Einzelzellen basierende Klone | |
| 1 Fläschchen | |
| CRTH2, GPR44 | |
| U2OS | |
| GPCRs |
| Zellbasierte Beta-Arrestin-Rekrutierung | |
| Tango™ GPR44 (CRTH2)-bla U2OS-Zellen werden auf Trockeneis geliefert (8 x 10^6 Zellen⁄Fläschchen). Sofort nach Erhalt in Flüssigstickstoff lagern oder zur sofortigen Verwendung auftauen. | |
| Fluoreszent | |
| G-Protein-gekoppelter Rezeptor (GPCR) | |
| Tango™ | |
| Endpunkt | |
| Teilende Zellen | |
| Tango™ |
For Research Use Only. Not for use in diagnostic procedures.