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R&D Systems™ Quantikine Immunoassay Control 1137 for Human Serum TIM-1
Immunoassay control set for Human T Cell Immunoglobulin Mucin-1 protein
Marke: R&D Systems™ QC229
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Beschreibung
TIM-1 (T cell immunoglobulin and mucin domain 1), also known as KIM-1 and HAVcr1, is expressed on many immune cell types, epithelial cells. It binds to phosphatidylserine (PS), LMIR5/CD300b, TIM-1 (homophilic), TIM-4, IgA, glycoproteins of number of enveloped viruses. Its interaction with PS enables TIM-1 to mediate phagocytosis, clearance of apoptotic cells. TIM-1 signaling costimulates T cell activation, enhances Th2 cytokine production. TIM-1 serves as cellular entry receptor for hepatitis A virus, Ebolavirus and Marburgvirus. Polymorphisms are associated with susceptibility to atopy, autoimmunity, severe hepatitis A virus infection in humans. A soluble form of TIM-1 is elevated in urine during nephropathy.
- Storage: Store unopened product at 2 to 8°C. Do not use past expiration date.
Spezifikation
| Store the unopened product at 2°C to 8°C. Do not use past expiration date. | |
| 26762 (Human); 171283 (Mouse); 286934 (Rat); 102141332 (Cynomolgus Monkey) | |
| Immunoassay Control Set 920 | |
| T Cell Immunoglobulin Mucin-1 |
| Control Set for ELISA Kit | |
| For quantitative measurement of T cell immunoglobulin protein levels | |
| Human |
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