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Invitrogen™ Mouse HGFR/MET ELISA Kit
Mouse HGFR/MET quantitates mouse HGFR/MET in serum, plasma, supernatant.
Marke: Invitrogen™ EM37RBX10
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Beschreibung
Mouse HGFR/MET quantitates mouse HGFR/MET in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse HGFR/MET.
MET is a tyrosine kinase receptor for the hepatocyte growth factor. It is linked to functions such as cell proliferation, scattering, morphogenesis, and survival. Ligand binding at the cell surface induces autophosphorylation of MET that provides docking sites for downstream signaling molecules. After activation of the ligand, MET interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, and STAT3. There interactions lead to the activation of signaling cascades including RAS-ERK, PI3, kinase-AKT, and PLCgamma-PKC. MET plays a role in embryonic development including gastrulation, development of muscles and neurons, angiogenesis, and kidney formation. It also plays a role in adults including wound healing, organ regeneration, and tissue remodeling. MET has been linked to cancers including gastric, renal, and breast; therefore, making it a target for cancer therapeutics and diagnostic testing.
Spezifikation
| AI838057; auts9; bHLHe59; CG1705; CG1705 Genprodukt aus Transkript CG1705-RB; CG1705-PA; CG1705-PB; CMET; c-met; DFNB97; Dmel\CG1705; Dmel_CG1705; DmMet; EC 2.7.10.1; Hepatozyten-Wachstumsfaktorrezeptor; HGF; HGF-Rezeptor; HGF-Rezeptor c-Met; HGF/SF-Rezeptor; Hgfr; HGF-SF-Rezeptor; Jugendhormonresistenz; Met; Met; Met; Met Proto-Oncogen; Met Proto-Oncogene (Hepatozyten-Wachstumsfaktorrezeptor); met Proto-Oncogene Tyrosinkinase; MET Proto-Oncogene, Rezeptor-Tyrosin-Kinase; Met/Met1; Methopren-tolerant; Methopren-tolerant; Methopren-tolerantes Protein; Met-PA; Met-PB; Mett; Oncogene MET; Par4; Proto-Oncogene c-Met; RCCP2; Resistenz (1) jugendliches H; Resistenz gegen jugendliches Hormon; Rst(1)JH; sc MET; Scatter-Faktor-Rezeptor; SF-Rezeptor; Lösliches c traf; Tyrosin-Protein-Kinase Met | |
| 0.08 ng/mL | |
| ELISA | |
| Kolorimetrisches Mikrotiterplatten-Lesegerät | |
| MET | |
| <10% | |
| HRP | |
| Nur für Forschungszwecke | |
| 2 bis 8 °C | |
| 1 h 20 min |
| 0,082 bis 20 ng/ml | |
| Biotin | |
| Überstand | |
| P16056 | |
| <12% | |
| Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers | |
| 10 x 96 Tests | |
| Serum, 50 µL; Plasma, 50 µL; Supernatant, 50 µL | |
| c-Met | |
| 4 h 45 min |
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