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![Invitrogen KIT [V559D T670I] Recombinant Human Protein:Rekombinante Proteine](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-650.jpg)
Invitrogen™ KIT [V559D T670I] Recombinant Human Protein
KIT (c-KIT) is a proto-oncogene and a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Recombinant human KIT V559D T670I (544-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
594.00 CHF - 9000.00 CHF
Spezifikation
| Zur Verwendung mit (Anwendung) | Enzyme and Protein Activity Assay, Industrial and Applied Science, Kinase Assay, Kinase Biology, Kinase Proteins and Expression Reagents, Pharma and Biopharma, Protein Assays and Analysis, Protein Biology, Target and Lead Identification and Validation |
|---|---|
| Zusammensetzung | 50mM Tris-HCl pH 7.5, 150mM NaCl, 0.25mM DTT, 10mM glutathione, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol |
| Molekulargewicht | 75.3kDa |
| Lagerungsbedingungen | Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws. |
| Gen-Alias | PBT, SCFR, CD117 |
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|---|---|---|---|---|---|---|---|---|---|
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|
15418963
|
Invitrogen™
PV6316 |
10 μg |
594.00 CHF
10 Mikrogramm |
Verfügbar ab: 11-02-2025
Loggen Sie sich ein, um den Lagerbestand zu sehen |
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|
15428963
|
Invitrogen™
PV6317 |
100 μg |
2010.00 CHF
100 Mikrogramm |
Verfügbar ab: 11-02-2025
Loggen Sie sich ein, um den Lagerbestand zu sehen |
|||||
|
15438963
|
Invitrogen™
PV6318 |
1 mg |
9000.00 CHF
1 Milligramm |
Verfügbar ab: 11-02-2025
Loggen Sie sich ein, um den Lagerbestand zu sehen |
|||||
Beschreibung
KIT was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT together with its ligand regulates growth and activation of a variety of hemopoietic and non-hemopoietic cells. Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Recently, deregulation of the KIT receptor TK by the prevalent activation loop mutation D816V has served as a focal point in therapeutic strategies aimed at curbing neoplastic mast cell growth.
- Validated in LanthaScreen™ Kinase Binding Assay
- Protocols available for simple use and optimized performance
- Multiple pack sizes available for convenient use
Spezifikation
| Enzyme and Protein Activity Assay, Industrial and Applied Science, Kinase Assay, Kinase Biology, Kinase Proteins and Expression Reagents, Pharma and Biopharma, Protein Assays and Analysis, Protein Biology, Target and Lead Identification and Validation | |
| 75.3kDa | |
| PBT, SCFR, CD117 | |
| Human | |
| GST Tag |
| 50mM Tris-HCl pH 7.5, 150mM NaCl, 0.25mM DTT, 10mM glutathione, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol | |
| Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws. | |
| aa 544-end | |
| Recombinant |
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