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Gibco™ Human Oncostatin M (227 aa) Recombinant Protein, PeproTech®
E. coli Recombinant Protein
Marke: Gibco™ 300-10-50UG
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Beschreibung
Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activated T cells, monocytes and Kaposi's sarcoma cells, OSM can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi's sarcoma cells, but inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release (e.g. IL-6, GM-CSF and G-CSF) from endothelial cells, and enhances the expression of low-density lipoprotein receptors in hepatoma cells. OSM shares several structural and functional characteristics with LIF, IL-6, and CNTF.
Spezifikation
| P13725 | |
| protein with no preservative | |
| 25.7 | |
| 50 μg | |
| -20°C | |
| <1 EU/μg | |
| OSM | |
| Unconjugated | |
| AAIGSCSKEY RVLLGQLQKQ TDLMQDTSRL LDPYIRIQGL DVPKLREHCR ERPGAFPSEE TLRGLGRRGF LQTLNATLGC VLHRLADLEQ RLPKAQDLER SGLNIEDLEK LQMARPNILG LRNNIYCMAQ LLDNSDTAEP TKAGRGASQP PTPTPASDAF QRKLEGCRFL HGYHRFMHSV GRVFSKWGES PNRSRRHSPH QALRKGVRRT RPSRKGKRLM TRGQLPR | |
| ≥ 98% by SDS-PAGE gel and HPLC analyses. |
| ELISA, Functional Assay, Western Blot | |
| 5008 | |
| Human Oncostatin M (227 aa) | |
| E. coli | |
| RUO | |
| MGC20461; OncoM; oncostatin M; oncostatin-M; OSM | |
| Human | |
| Recombinant | |
| Lyophilized |