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Herbimycin A, Tocris Bioscience™
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Menge:
100 μg
Beschreibung
Herbimycin A is an ansamycin antibiotic that acts as a Src family kinase inhibitor. Binds to the SH domain and inhibits the activity of p60v-src and p210BCR-ABL. Exhibits antiangiogenic activity in endothelial cells in vitro. Also inhibits Hsp90 and impairs recovery from heat shock.
Spezifikation
Spezifikation
| Chemischer Name oder Material | Herbimycin A |
| Typ | Herbimycin A |
| CAS | 70563-58-5 |
| Summenformel | C30H42N2O9 |
| Synonym | (15R)-17-demethoxy-15-methoxy-11-O-methyl-geldanamycin |
| InChI-Schlüssel | MCAHMSDENAOJFZ-HYKLGOSOSA-N |
| SMILES | CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C=C(C1OC)C2=O)C)OC)OC(=O)N)C)C)OC)OC |
| IUPAC-Name | [(2S,3R,6S,7R,8E,10R,12E,14E)-2,5,6,11-tetramethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-17-azabicyclo[16.3.1]docosa-1(21),8,12,14,18-pentaen-10-yl] carbamate |
| Molekulargewicht (g/mol) | 574.671 |
| PubChem CID | 133268477 |
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