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GRI 977143, Tocris Bioscience™
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Menge:
10 mg
50 mg
Beschreibung
Selective lysophosphatidic acid 2 (LPA2) receptor non-lipid agonist (EC50 = 3.3 μM). Does not activate other LPA GPCRs at concentrations up to 10 μM. Antiapoptotic; inhibits activation of caspases 3, 7, 8 and 9, Bax translocation and PARP-1 cleavage. Activates ERK1/2 survival pathway.
Spezifikation
Spezifikation
Chemischer Name oder Material | GRI 977143 |
Menge | 50 mg |
Formelmasse | 391.44 |
Reinheit (%) | >98% |
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