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Thermo Scientific™ GeneBLAzer™ P2RY11-NFAT-bla CHO-K1 Cells
GeneBLAzer™ P2RY11-NFAT-bla CHO-K1 cells contain the human Purinergic receptor P2, G protein-coupled, 11 (P2RY11) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.
Marke: Thermo Scientific™ K1729
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Beschreibung
GeneBLAzer™ P2RY11-NFAT-bla CHO-K1 cells contain the human Purinergic receptor P2, G protein-coupled, 11 (P2RY11) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line. CellSensor™ NFAT-bla CHO-K1 cells (Cat. No. K1534) contain a beta-lactamase reporter gene under control of the Nuclear Factor of Activated T-cells (NFAT) response element.
The GeneBLAzer™ P2RY11-NFAT-bla CHO-K1 cells are functionally validated for Z' and EC50 concentrations of ATP. In addition, GeneBLAzer™ P2RY11-NFAT-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.
P2RY11 expression is broadly distributed and has been found in the brain, pituitary, lymphocytes, spleen, intestines, macrophages, lung, stomach, adipose tissue, pancreas, kidney, prostate, heart, placenta, liver, and skeletal muscle. Differentiation of human promyelocytic HL60 cells and maturation of monocyte-derived dendritic cells have been shown to be mediated by ATP activation of P2RY11.
For Academic pricing please login or contact us at discoverysciences@invitrogen.com.
Spezifikation
| NM_002566.4 | |
| Teilende Zellen | |
| Fluoreszent | |
| P2RY11 | |
| Auf Einzelzellen basierende Klone | |
| 2 x 106 Zellen | |
| P2RY11 | |
| CHO-K1 | |
| GPCRs |
| Zellbasiertes Beta-Lactamase-Reportergen | |
| Inhalt: K1729 GeneBLAzer™ P2RY11-NFAT-bla CHO-K1-Zellen (LiveBLAzer™-FRET B⁄G Ladekit, Lösung D und andere Materialien sind separat erhältlich; siehe Protokoll). Enthält: • GeneBLAzer™ P2RY11-NFAT-bla CHO-K1-Zellen • GeneBLAzer™ P2RY11-NFAT-bla CHO-K1 Assay-Protokoll • Analysenzertifikat Lagerung: Die GeneBLAzer™ P2RY11-NFAT-bla CHO-K1-Zellen werden auf Trockeneis geliefert und sollten sofort nach Erhalt in flüssigem Stickstoff gelagert werden. |
|
| FRET | |
| P2RY11-NFAT-bla CHO-K1-Zellen, P2RY11-NFAT-bla CHO-K1-Assay-Protokoll, Analysenzertifikat | |
| GeneBLAzer™ | |
| BLA (Beta-Lactamase) | |
| Teilende Zellen | |
| GeneBLAzer™ |
Nur für Forschungszwecke. Nicht zur Verwendung bei diagnostischen Verfahren.