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Tocris Bioscience™ Geldanamycin
Selective Hsp90 inhibitor
Marke: Tocris Bioscience™ 1368/1
424.07 CHF gültig bis 2024-12-16
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Beschreibung
Selectively inhibits heat shock protein 90 (Hsp90). Binds to the ATP site of Hsp90 (Kd = 1.2 μM) and inhibits its chaperone activity. Consequently inhibits activities of oncogenic kinases (e.g. src, Raf), p53 and steroid receptors. Demonstrates antiproliferative effect on breast cancer stem-like cells.Spezifikation
| 1 mg | |
| >98% | |
| C29H40N2O9 | |
| Soluble to 10 mM in DMSO |
| Desiccate at -20°C | |
| 30562-34-6 | |
| 560.64g/mol |