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GAPDH Loading Control Monoclonal Antibody (GA1R), HRP, Invitrogen™

Mouse Monoclonal Antibody

Marke:  Invitrogen MA515738HRP


Artikelnummer. 15269204

  • 340.00 CHF / 1 Stück
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Beschreibung

Beschreibung

MA5-15738-HRP has been successfully used in Western blotting applications with yeast, bacteria, insect, human, mouse, rat, rabbit, hamster, and chicken samples.

GAPDH (Glyceraldehyde-3-phosphate dehydrogenase) is a catalytic enzyme commonly known to be involved in glycolysis. GAPDH exists as a tetramer of identical 37-kDa subunits and catalyzes the reversible reduction of 1,3-bisphosphoglycerate to glyceraldehyde 3-phosphophate in the presence of NADPH. Apart from playing a key role in glycolysis, GAPDH is ubiquitously expressed and displays other activities unrelated to its glycolytic function. GAPDH is reported to be involved in the processes of DNA replication, DNA repair, nuclear RNA export, membrane fusion and microtubule bundling. Studies provide evidence of GAPDH playing an essential part in gene expression observed in apoptosis and as part of the cellular phenotype of age-related neurodegenerative diseases. Further, GAPDH is involved in other cellular processes ranging from membrane fusion, and neuronal apoptosis in cancer. GAPDH is reported to bind to a variety of other proteins, including the amyloid precursor protein, mutations in which cause some forms of Alzheimer's disease (AD), and the polyglutamine tracts of Huntingtin, the protein product aberrant forms of which are causative of Huntington's disease. Associations between GAPDH, actin and tubulin have also be reported. Since GAPDH is expressed at high levels in most tissues, it is useful as protein loading control in Western Blot analysis.
TRUSTED_SUSTAINABILITY
Spezifikation

Spezifikation

GAPDH Loading Control
Monoclonal
1 mg/mL
antibody with 0.07% Kathon
O14556, P00356, P04406, P04797, P16858, P17244, P46406, Q64467, Q9ESV6
GAPDH, GAPDHS
Recombinant GAPDH
50 μL
Primary
Bacteria, Chicken, Hamster, Human, Insect, Mouse, Rabbit, Rat, Yeast
Antibody
IgG1
Western Blot
GA1R
HRP
GAPDHS
38 kDa BFA-dependent ADP-ribosylation substrate; aging-associated gene 9 protein; BARS-38; bb02e05; cb350; cb609; CDABP0047; EC 1.2.1.12; epididymis secretory protein Li 278; epididymis secretory sperm binding protein Li 162eP; fb71f08; fk58c09; G3PD; G3PDH; GAPD; GAPD2; gapdh; GAPDH2; GAPDH-2; GAPDHS; Gapds; Gapd-s; glceraldehyde-3-phosphate dehydrogenase; glyceraldehyde 3-phosphate dehydrogenase; glyceraldehyde 3-phosphate dehydrogenase, testis-specific; glyceraldehyde phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase (G3PDH); glyceraldehyde-3-phosphate dehydrogenase 2; glyceraldehyde-3-phosphate dehydrogenase GAPDH; glyceraldehyde-3-phosphate dehydrogenase like-17 protein; glyceraldehyde-3-phosphate dehydrogenase type 2; glyceraldehyde-3-phosphate dehydrogenase, spermatogenic; glyceraldehyde-3-phosphate dehydrogenase, testis-specific; glyceraldehyde-phosphate-dehydrogenase; glycerine aldehyde 3-phosphate dehydrogenase; HEL-S-
Mouse
Protein A
RUO
100009074, 100352213, 100736557, 100767862, 14433, 14447, 24383, 2597, 26330, 374193, 66020
4° C
Liquid
Produktvorschläge

Produktvorschläge

Videos
Sicherheit und Handhabung

Sicherheit und Handhabung

Produktidentifikator
  • GAPDH Loading Control Monoclonal Antibody (GA1R), HRP

Signalwort
  • Achtung

Gefahrenkategorie
  • Sensibilisierung der Haut Kategorie 1

Gefahrenhinweis
  • H317-Kann allergische Hautreaktionen verursachen.

Sicherheitshinweis
  • P260-Staub/Rauch/Gas/Nebel/Dampf/Aerosol nicht einatmen.
  • P303+P361+P353-BEI BERÜHRUNG MIT DER HAUT (oder dem Haar): Alle kontaminierten Kleidungsstücke sofort ausziehen. Haut mit Wasser abwaschen/duschen.
  • P501b-Inhalt/Behälter gemäß den örtlichen/regionalen/nationalen/internationalen Vorschriften zuführen.

Ergänzende Informationen
  • MIXTURE LIST-Enthält: 5-chloro-2-methyl-4-isothiazolin-3-one,2-methyl-2H-isothiazol-3-one

Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote