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CASK Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marke: Invitrogen PA596141
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Beschreibung
Immunogen sequence: MADDDVLFED VYELCEVIGK GPFSVVRRCI NRETGQQFAV KIVDVAKFTS SPGLSTEDLK REASICHMLK HPHIVELLET YSSDGMLYMV FEFMDGADLC FEIVKRADAG FVYSEAVASH YMRQILEALR YCHDNNIIHR DVKPHCVLLA SKENSAPVKL GGFGVAIQLG ESGLVAGGRV GTPHFMAPEV VKREPYGKPV DVWGCGVILF ILLSGCLPFY GTKERLFEGI IKGKYKMNPR QWSHISESAK DLVRRMLMLD PAERITVYEA LNHPWLKERD RYAYKIHLPE TVEQLRKFNA; Positive Samples: 293T, U-251MG, BxPC-3, 22Rv1, NCI-H460, A-549; Cellular Location: Cell membrane, Cytoplasm, Nucleus, Peripheral membrane protein
CASK is a calcium/calmodulin-dependent serine protein kinase which is a MAGUK (membrane-associated guanylate kinase) protein family member. CASK is a scaffold protein and the encoded protein is located at synapses in the brain. CASK associates with FG syndrome 4, mental retardation, microcephaly with pontine and cerebellar hypoplasia, and a form of X-linked mental retardation. CASK functions as a cytoskeletal membrane scaffold that coordinates signal transduction pathways within the cortical cytoskeleton.
Spezifikation
| CASK | |
| Polyclonal | |
| Unconjugated | |
| Cask | |
| CAGH39, calcium/calmodulin dependent serine protein kinase, calcium/calmodulin-dependent serin protein kinase, Calcium/calmodulin-dependent serine protein kinase, calcium/calmodulin-dependent serine protein kinase (MAGUK family), calcium/calmodulin-dependent serine protein kinase membrane-associated guanylate kinase, CAMGUK, CASK, CMG, DXPri1, DXRib1, FGS4, G-protein-coupled receptor GPR34, hCASK, LIN2, LIN-2, MGC7449, MICPCH, mLin-2, MRXSNA, OTTHUMP00000023157, OTTHUMP00000023161, OTTHUMP00000023162, Pals3, peripheral plasma membrane protein CASK, Protein lin-2 homolog, RP23-278L4.1, TNRC8, trinucleotide repeat containing 8 | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 8573 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Immunocytochemistry, Western Blot | |
| 0.67 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide, pH 7.3 | |
| O14936 | |
| Cask | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human CASK (NP_0011195261) | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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