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Bumetanide, Tocris Bioscience™
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Menge:
50 mg
Beschreibung
Bumetanide is a loop diuretic that inhibits the Na+/2Cl-/K+ (NKCC) cotransporter. More potent than furosemide (Cat. No. 3109). Bumetanide improves electrophysiological, pathological and cognitive deficits in APOE4 knock-in mice. RNA sequencing of neurons derived from APOE4 induced pluripotent stem cell (iPSC) shows Bumetanide reverses Alzheimer's disease transcriptomic signatures.
Spezifikation
Spezifikation
| Chemischer Name oder Material | Bumetanide |
| CAS | 28395-03-1 |
| Summenformel | C17H20N2O5S |
| Menge | 50 mg |
| Synonym | bumetanide, 3-butylamino-4-phenoxy-5-sulfamoylbenzoic acid, bumex, burinex, fordiuran, lunetoron, fontego, segurex, bumetanida, bumetanidum |
| InChI-Schlüssel | MAEIEVLCKWDQJH-UHFFFAOYSA-N |
| SMILES | CCCCNC1=C(C(=CC(=C1)C(=O)O)S(=O)(=O)N)OC2=CC=CC=C2 |
| IUPAC-Name | 3-(Butylamin)-4-Phenoxy-5-Sulfamoylbenzoesäure |
| Molekulargewicht (g/mol) | 364.416 |
| PubChem CID | 2471 |
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