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ATP6V1C2 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marke: Invitrogen PA522131
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Beschreibung
Recommended positive controls: 293T, A431, H1299, HeLa, Molt-4, Raji. Predicted reactivity: Mouse (89%), Rat (90%), Bovine (92%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
ATP6V1C2 encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain C subunit isoforms.
Spezifikation
| ATP6V1C2 | |
| Polyclonal | |
| Unconjugated | |
| Atp6v1c2 | |
| 1110038G14Rik; Atp6c2; Atp6v1c2; ATPase H+ transporting V1 subunit C2; ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2; ATPase, H+ transporting, lysosomal V1 subunit C2; ATPase, H+ transporting, V1 subunit C, isoform 2; vacuolar H+ ATPase C2; vacuolar proton pump subunit C 2; V-ATPase C2 subunit; V-ATPase subunit C 2; VMA5; V-type ATPase C2 subunit a isoform; V-type proton ATPase subunit C 2 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 245973 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot | |
| 1 mg/mL | |
| 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7 | |
| Q8NEY4 | |
| Atp6v1c2 | |
| Recombinant fragment corresponding to a region within amino acids 3 and 237 of V-ATPase C2 (Uniprot ID#Q8NEY4) | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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